Creative Biogene is a forward-looking service provider in mRNA research and development. With years of accumulation in this field, we have established a range of mature platforms to meet the high requirements of the development of mRNA-based drugs.

Custom mRNA synthesis platform

Based on an efficient in vitro transcription methodology and state-of-the-art facilities, Creative Biogene has developed a dedicated platform to customize highly modified pharmaceutical mRNAs. We have the capability to produce high-quality mRNAs from milligrams to multi-grams in scales, and a few hundred nucleotides to more than 10 kilobases in length. We focus our attention on service quality, speed, and customers' project needs and budget.

mRNA-based drug pharmacology optimization platform

To overcome the inherent of new drug classes and expand the potential application of mRNA-based therapy, we have developed a pharmacology optimization platform. We focus on the stability and immunogenicity of mRNA and provide corresponding strategies, including mRNA molecular stabilization and formulation strategies.

mRNA-based drug pharmacology optimization platform

Delivery nanosystem platform

Available delivery systems adapted to their features and purpose are in demand to efficiently deliver mRNA intracellularly for clinical applications. On our platform, we are committed to providing advanced delivery systems, nanosystems with greater payload capacity, involving lipid nanoparticles (LNPs), polymeric nanoparticles (PNPs) and lipid-polymer nanoparticles (LPNs). We focus on high encapsulation efficiency, scalability of production and low maintenance cost, and our technologies are at the forefront of the mRNA-based drug research and development field.

Nanoparticle characterization platform

Creative Biogene is committed to accelerating the project requiring efficient delivery of mRNA into target cells in vivo. Apart from providing advanced delivery nanocarriers in a high-quality, scalable and economical way, we also have developed a platform to implement characterization of these nanoparticle carriers for mRNA-based drug delivery, involving physicochemical characterization, stability of mRNA-nanoparticles and other characterizations.

Emerging infectious disease response platform

With the growing threat of infectious diseases, rapid and efficient vaccines are urgently needed to provide a frontline defense against disease transmission. The mRNA-based technologies are promising in infectious disease prophylaxis. Based on the robust and systematic mRNA vaccine development platform, Creative Biogene has the capability to quickly develop mRNA vaccines against key targets of pathogens. We focus on the mRNA-expressed antibody used for emerging infections disease, offering a one-stop solution based on the mRNA-expressed antibody to rapidly treat the new pathogen and prevent its transmission.

Infectious disease response platform

Professionalism, high-quality and excellent service are key words in the relationship between Creative Biogene and our global customers. To initiate or advance your project, please don't hesitate to contact us. We are glad to cooperate with you!

For research use only. Not intended for any clinical use.
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